All of my original images don't get touched/altered, I import them into Lightroom and export Tiff's and Jpeg's to work on. The first way I have found to reduce noise is to export as a 16 bit Tiff. Then in photoshop change the bit amount to 8 bit so the plug-in will work. This saves quite a lot of detail.
These images were done before I came up with the 16bit tiff idea. They only show what detail can be found in images that may look rather poor to begin with. They were all taken during a 3 hour Eco Cruise around the Tasman Peninsula coastline. During this trip I felt rather sea sick due to the fact I was forever taking photos. In other words, I was always looking through the view finder. This had an adverse effect on me. I didn't feel too good by the end of it but the trip was well worth it!